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U.S. National Institutes of Health
Last Updated: 03/05/10

CDP New Grants for Fiscal Year 2000

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Abstracts of these funded grants are entered in the CRISP (Computer Retrieval of Information on Scientific Projects) database of federally funded biomedical research projects at This searchable database can be used to retrieve abstracts by grant number, principal investigator or other search terms. It also contains abstracts for grants funded in earlier fiscal years.

Hint: In the NCI Funded Research Portfolio Database, use the Cancer Activity search term to locate grants pertaining to Diagnosis, Technology Development or Resources Development. Use the Mechanism search term to limit your search to Exploratory/Developmental (R21) grants, regular Research Project (R01) grants or Program Project (P01) grants.

Cooperative Agreement (U01) Grants Awarded in Response to RFA CA98-027, Director's Challenge: Toward a Molecular Classification of Tumors

Leonard H. Augenlicht, Ph.D.
Molecular Classification of Colon Tumors
Montefiore Medical Center, Bronx, NY

Jeffrey A. Boyd, Ph.D.
Molecular Classification of Ovarian Cancers
Sloan-Kettering Institute for Cancer Research, New York, NY

Sanford D. Markowitz, M.D., Ph.D.
Gene Expression of Colon Cancers that Metastasize
Case Western Reserve University, Cleveland, OH

George K. Michalopoulos, M.D., Ph.D.
Molecular Reclassification of Prostatic Cancer
University of Pittsburgh, Pittsburgh, PA

Stanley F. Nelson, M.D.
Gene Expression Based Classification of Glial Tumors
University of California Los Angeles, Los Angeles, CA

Greg J. Riggins, M.D., Ph.D.
A Molecular Classification of Brain Tumors
Duke University, Durham, NC

Timothy J. Triche, M.D., Ph.D.
Gene Expression in Sarcomas of Childhood and Adolescence
Children's Hospital of Los Angeles, Los Angeles, CA

Cheryl L. Willman, M.D.
Molecular Taxonomy of Pediatric and Adult Acute Leukemia
University of New Mexico, Albuquerque, NM

Timothy J. Yeatman, M.D.
Decoding Fingerprints Portending Colon Cancer Metastasis
University of South Florida, Tampa, FL

Cooperative Agreement (U01) Grants Awarded in Response to RFA CA99-012, Cooperative Prostate Cancer Tissue Resource

Michael J. Becich, M.D., Ph.D.
A Shared Tissue Resource for the Molecular Classifaction
University of Pittsburgh, Pittsburgh, PA

Andre A. Kajdacsy-Balla, M.D., Ph.D.
Facilitating Discovery through a Human Prostate Tissue Resource
Medical College of Wisconsin, Milwaukee, WI

Jonathan Melamed, M.D.
NYU Cooperative Prostate Cancer Tissue Resource
New York University School of Medicine, New York, NY

Jan M Orenstein, M.D., Ph.D.
Mid Atlantic Prostate Cancer Bank
George Washington University, Washington, DC

Exploratory Grants (R21) Awarded in Response to PA-98-022, Exploratory Studies in Cancer Diagnostics

Leo L. Cheng, Ph.D.
Characterization of Prostate Cancer With HRMAS 1HMRS
Massachusetts General Hospital, Charlestown, MA

Eleftherios P. Diamandis, M.D.
A Candidate New Biomarker for Breast Cancer Diagnosis
Mount Sinai Hospital, Toronto, Ontario, Canada

Max Diem, Ph.D.
Detection of Cancerous Cells Via FT IR Microscopy
Hunter College, New York, NY

Kojo S. Elenitoba-Johnson, M.D.
Expression Profiling of Progressed Follicular Lymphomas
University of Utah, Salt Lake City, UT

Michael S. Kinch, Ph.D.
EphA2--a Marker of Breast Cancer Progression
Purdue University, West Lafayette, IN

Mary J. Murnane, Ph.D.
Cathepsin B/Mmp 9 Profiles--Predicting Colorectal Cancer
Boston University, Boston, MA

James C. Willey, M.D.
Gene Expression Indices Associated With Chemoresistance
Medical College of Ohio, Toledo, OH

Bradford E. Windle, Ph.D
hTERT Expression as a Marker for Early Cancer Detection.
Virginia Commonwealth University, Richmond, VA

Yan Xu, Ph.D.
New Method for the Early Detection of Ovarian Cancer
Cleveland Clinic Foundation, Cleveland OH

Martha A. Zeiger, M.D.
hTERT Gene Expression in Suspicious Thyroid FNA Samples
Johns Hopkins University, Baltimore, MD

R21 Grants Awarded in Response to PA-98-042, Exploratory Grants for Correlative Laboratory Studies and Clinical Trials

Samuel B. Ho, M.D.
Detection and Prognosis of Gastrointestinal Cancer
University of Minnesota Twin Cities, Minneapolis, MN

Gary L. Johanning, Ph.D.
HPV Oncoprotein Expression in Cervical Cancer
University of Alabama at Birmingham, Birmingham, AL

R21 Award in Response to PA-98-099, Correlative Studies Using Specimens from Multi-Institutional Treatment Trials

Sui Huang, M.D., Ph.D.
Perinucleolar Compartment as a Putative Cancer Marker
Northwestern University, Chicago, IL

R21 Grants Awarded in Response to PAR-99-100, Innovative Technologies for the Molecular Analysis of Cancer: Phased Innovation Award (R21/R33)

Mark S. Chee, Ph.D.
Protein Profiling Arrays
Illumina, Inc., San Diego, CA

Gary A. Churchill, Ph.D.
Experimental Design & Analysis for Expression Microarray
Jackson Laboratory, Bar Harbor, ME

Xiang-Dong Fu, Ph.D.
Cancer Classification Based on mRNA Isoforms
University of California, San Diego, CA

Peter R. Gascoyne, Ph.D.
Integrated Isolation & Molecular Analysis of Tumor Cells
University of Texas MD Anderson Cancer Center, Houston, TX

Ian W. Hunter, Ph.D.
Androgen Receptor Biochips--Prostate Cancer Management
Massachusetts Institute of Technology, Cambridge, MA

Arun Majumdar, Ph.D.
Optomechanical Chips for Molecular Profiling of Cancer
University of California, Berkeley, CA

Sherman M. Weissman, M.D.
Display Methods for Surveying Mutations
Yale University, New Haven, CT

R21 and R33 Grants Awarded in Response to PAR-99-102, Applications of Innovative Technologies for the Molecular Analysis of Cancer: Phased Technology Application Award (R21/R33)

Graham J. Brock, Ph.D.
Identification of m5CpG Alterations in Breast Carcinomas
University of Glasgow, Glasgow, United Kingdom

Sandra L. Dabora, M.D., Ph.D.
Mutant Analysis of TSC1 & TSC2 in TSC Related Disorders
Brigham and Women's Hospital, Boston, MA

James M. Gale, Ph.D.
Molecular Staging of Human Squamous Cell Skin Cancer
University of New Mexico, Albuquerque, NM

Jeffrey K. Griffith, Ph.D.
Prognostic Value of Telomere DNA in Prostate Biopsy
University of New Mexico, Albuquerque, NM

Maria Pallavicini, Ph.D.
Protein Signatures of Leukemic Cells
University of California, San Francisco, CA

Indra Poola, Ph.D.
Molecular Assay For Estrogen Receptors in Breast Tumors
Howard University, Washington, DC

Heinz-Ulrich G. Weier, Ph.D.
Spectral Imaging for Phenotype Analysis of Cancer Cells
University of California-Lawrence Berkeley National Laboratory, Berkeley, CA

R21 and R33 Grants Awarded in Response to PAR-98-067, Innovative Technologies for the Molecular Analysis of Cancer: Phased Innovation Award

Tim H-M. Huang, Ph.D.
High Throughput Methylation Analysis in Cancer
University of Missouri, Columbia, MO

Deirdre R. Meldrum, Ph.D.
Automated Minimal Residual Disease Quantification
University of Washington, Seattle, WA

R21 Grant Awarded in Response to PAR-99-128, Insight Awards to Stamp Out Breast Cancer

Charles B. Grissom, Ph.D.
Fluorescent Markers for Breast Cancer Surgery
University of Utah, Salt Lake City, UT

Research Grants (R01) Awarded in Response to PAR-99-009, Bioengineering Research Grants

Leonard A. Herzenberg, Ph.D.
Multi Colors FACS--Advancement for Extended Applications
Stanford University, Stanford, CA

Kenneth K. Wang, M.D.
A Novel Technique For Screening Barrett's Esosphagus
Mayo Clinic, Rochester, MN

Resource Related Research Project (R24) Grant Awarded in Response to PAS 99-010, Bioengineering Research Partnerships

Steven A. Soper, Ph.D.
Micro-Instrument Platforms for Genetic-Based Analyses
Louisiana State Univ A&M Col, Baton Rouge, LA

Investigator-Initiated Research Project Grants Awarded in Fiscal Year 2000

Regular (R01) Research Grants

Gail M. Clinton, Ph.D.
Truncated HER 2/neu Protein in Breast Cancer
Oregon Health Sciences University, Portland, OR

Zbigniew Darzynkiewicz, M.D., Ph.D.
Probes For Cytometry
New York Medical College, Hawthorne, NY

Louis Dubeau, M.D., Ph.D.
Telomerase Assay for Ovarian Cancer Detection
University of Southern California, Los Angeles, CA

Richard Everson, M.D.
Receptor Gene Polymorphisms in Prostate Cancer
Wayne State University, Detroit, MI

Michael S. Feld, Ph.D.
Real Time in Vivo Diagnosis of Dysplasia by Fluorescence
Massachusetts Institute of Technology, Cambridge, MA

Rafael Fonseca, Ph.D.
Chromosomal Abnormalities in Myeloma as Detected By FISH
Mayo Clinic, Rochester, MN

Robert H. Getzenberg, Ph.D.
Characterization of the Bladder Cancer NMP, BLCA-4
University of Pittsburgh, Pittsburgh, PA

Ingegerd Hellstrom, M.D., Ph.D.
Mesothelin Antigens for Diagnosis/Therapy of Ovarian Cancer
Pacific Northwest Research Institute, Seattle, WA

Robert B. Jenkins, M.D.
Genetic and Biologic Studies of 1p and 19q in Gliomas
Mayo Clinic, Rochester, MN

David N. Louis, M.D.
Chromosome 19q Glioma Tumor Suppressor Gene
Massachusetts General Hospital, Boston, MA

Steven M. Powell, M.D.
Genetic Alterations in Gastric Carcinomas
University of Virginia, Charlottesville, VA

Alphonse E. Sirica, Ph.D.
Altered Growth Factor Pathways in Billiary Cancer
Virginia Commonwealth University, Richmond, VA

Chung S. Yang, Ph.D.
Mechanisms of Human Esophageal Carcinogenesis
Rutgers The State Univ of NJ, New Brunswick, NJ

Phase II or Fast-Track SBIR Grants (R44)

Steven A. Bogen, M.D., Ph.D.
Synthetic Controls for Immunohistochemical Assays
Cytologix Corporation, Cambridge, MA

Eric R. Craine, Ph.D.
A Non Invasive Dermatological Lesion Classifier
Western Research Company, Inc., Tucson, AZ

R. Hugh Daniels, Ph.D.
Sensitive, Multiplexed Analysis of Breast Cancer Markers
Quantum Dot Corporation, Hayward, CA

Raymond L. Houghton, Ph.D.
Novel Genes for the Diagnosis/Prognosis of Breast Cancer
Corixa Corporation, Seattle, WA

Richard M. Levenson, M.D.
Simple, Low-Cost, Ultra-Rapid Spectral Imaging Platform
Cambridge Research and Instrumentation, Boston, MA

James L. Prescott, Ph.D.
p53 Mutation Analysis for Bladder Cancer Prognosis
Urocor, Inc., Oklahoma City, OK

Douglas R. Smith, Ph.D.
Low-Cost, Sequence-Based Cancer Pharmacogenetics
Genome Therapeutics Corporation, Waltham, MA

Jan Trnovsky, Ph.D.
Rare Cancer Cell Detection Method
One Cell Systems, Inc., Cambridge, MA

Mary-Anne V. Watt, Ph.D.
High Sensitivity, Ultra-Low Background DNA Chips
Mirus Corporation, Madison, WI

Hong Zhang, Ph.D.
ANN Software for Early Detection of Ovarian Cancer
Horus Global Healthnet, Inc., Hilton Head Island, SC